Catalytic properties of mouse carbonic anhydrase V.

Carbonic anhydrase-azosulfonamide complexes. Spectral properties.

Metal binding and catalytic activity in bovine carbonic anhydrase.

Carbonic anhydrase was the earliest known zinc metallo-enzyme (4). It has been isolated from various sources, mainly mammalian red blood cells (see (5)). Although several methods for the preparation of highly active enzyme were described earlier, adequate purification was not achieved nor was the stoichiometry of zinc established (5). Recently, bovine erythrocyte carbonic anhydrase, homogeneous...

Organization of the mouse and human carbonic anhydrase II genes.

The carbonic anhydrase (CA) multigene family is beginning to appear more complex than was considered possible during the earlier days of work on the different isozymes. The two classic erythrocyte isozymes found in amniotes, CA I and CA 11, have been studied in considerable detail in terms of their kinetics, structures, and Within the last few years, at least one other isozyme (CA 111), which i...

Expression of carbonic anhydrase IV in mouse placenta.

Carbonic anhydrase (CA) facilitates acid-base transport in several tissues. Acidosis upregulates membrane-bound SDS-resistant hydratase activity in various tissues and CA IV mRNA in rabbit kidney. This study was designed to assess whether the expression of membrane-bound CA IV isozyme in mouse placenta is regulated developmentally and by maternal ammonium chloride loading at the end of pregnanc...

Properties of a carbonic anhydrase inhibitor protein in flounder serum.

The blood serum of the European flounder Platichthys flesus strongly inhibits soluble erythrocytic carbonic anhydrase from the same species. The inhibition is of the uncompetitive type. Hence, the mechanism of the carbonic anhydrase inhibition is different from that of all other known carbonic anhydrase inhibitors. The serum showed no inhibitory effect on carbonic anhydrase from human and bovin...